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Vanderbilt study questions accuracy of lung cancer screens in some geographic regions
NCI Cancer Center News
(Posted: 09/24/2014) - A new analysis of published studies found that FDG-PET technology is less accurate in diagnosing lung cancer versus benign disease in regions where infections like histoplasmosis or tuberculosis are common.

NIH exceptional responders to cancer therapy study launched
NCI Press Release
(Posted: 09/24/2014) - The Exceptional Responders Initiative, a study to investigate the molecular factors of tumors associated with exceptional treatment responses of cancer patients to drug therapies, was launched today by NCI. Scientists will attempt to identify the molecular features of tumors that predict whether or not a particular drug or class of drugs will be beneficial.
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Massachusetts General mouse study reveals gene expression patterns in pancreatic CTCs
NCI Cancer Center News
(Posted: 09/23/2014) - Analysis of circulating tumor cells (CTCs) in a mouse model of pancreatic cancer identified distinct patterns of gene expression in several groups of CTCs, including significant differences from the primary tumor that may contribute to the ability to generate metastases.

Dana-Farber researchers articulate the fine line between breast cancer and normal tissues
NCI Cancer Center News
(Posted: 09/23/2014) - Up to 40 percent of patients undergoing breast cancer surgery require additional operations because surgeons may fail to remove all the cancerous tissue in the initial operation.

U of Pittsburgh researchers potentially find a better way to track emerging cell therapies using MRIs
NCI Cancer Center News
(Posted: 09/22/2014) - Researchers describe the first human tests of using a perfluorocarbon (PFC) tracer in combination with non-invasive magnetic resonance imaging (MRI) to track therapeutic immune cells injected into patients with colorectal cancer.

UPenn researchers find that in mouse study, exercise added to chemo shrinks tumors faster
NCI Cancer Center News
(Posted: 09/22/2014) - Adding exercise to a regimen of chemotherapy shrinks tumors more than chemotherapy alone, according to a study with mice.

Stanford researchers create evolved protein in mice that may stop cancer from spreading
NCI Cancer Center News
(Posted: 09/22/2014) - Stanford researchers have created a decoy protein designed to interrupt the signaling pathway that triggers the breakaway of cancerous cells; in other words the signal that initiates metastasis.

MD Anderson researchers find that cancer cells adapt energy needs to spread illness to other organs
NCI Cancer Center News
(Posted: 09/22/2014) - Scientists at The University of Texas MD Anderson Cancer Center have found that cancer cells traveling to other sites have different energy needs from their “stay-at-home” siblings which continue to proliferate at the original tumor site.

NCI’s Center for Global Health announces first major research grants to support portable technologies
NCI News Note
(Posted: 09/22/2014) - NCI’s Center for Global Health announced grants that will support the development and validation of low-cost, portable technologies. These technologies have the potential to improve early detection, diagnosis, and non-invasive or minimally invasive treatment of several cancer types that have a particularly high prevalence in a number of low- and middle-income countries.
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St. Jude researchers find that improved risk identification will aid fertility preservation in young male cancer patients
NCI Cancer Center News
(Posted: 09/17/2014) - St. Jude Children’s Research Hospital study has identified the cumulative dose of a widely used class of chemotherapy drugs that leaves young male cancer patients at risk for impaired sperm production as adults.

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