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Seven potential immunotherapy targets for treatment of melanoma identified
NCI News Note
(Posted: 09/10/2013) - NCI scientists, using a unique digital technology that counts RNA molecules in small amounts of tumor tissue, identified seven potential immunotherapy targets for treatment of melanoma.

Researchers uncover genetic cause of childhood leukemia
NCI Cancer Center News
(Posted: 09/09/2013) - For the first time, a genetic link specific to risk of childhood leukemia has been identified, according to a team of researchers from Memorial Sloan-Kettering Cancer Center, St. Jude Children's Research Hospital, University of Washington (an affiliate of the Fred Hutchinson Cancer Research Center), and other institutions. The discovery was reported online in the journal Nature Genetics.

Study uncovers value of mammogram screening for younger women
NCI Cancer Center News
(Posted: 09/09/2013) - A new analysis has found that most deaths from breast cancer occur in younger women who do not receive regular mammograms. Among 609 confirmed breast cancer deaths, 29 percent were among women who had been screened with mammography, while 71 percent were among unscreened women. The study, led by scientists at the Harvard Medical School in Boston (a component of the Dana-Farber Cancer Institute) was published early online in CANCER, a peer-reviewed journal of the American Cancer Society.

New laser-based tool could dramatically improve the accuracy of brain tumor surgery
NCI Cancer Center News
(Posted: 09/06/2013) - A new laser-based technology may make brain tumor surgery much more accurate, allowing surgeons to tell cancer tissue from normal brain at the microscopic level while they are operating, and avoid leaving behind cells that could spawn a new tumor. In a new paper, featured on the cover of the journal Science Translational Medicine, a team of scientists from the University of Michigan Medical School (home of the University of Michigan Comprehensive Cancer Center) and Harvard University (a component of the Dana-Farber Cancer Institute) researchers describes how the technique allows them to “see” the tiniest areas of tumor cells in brain tissue.

Some immune cells appear to aid cancer cell growth
NCI Cancer Center News
(Posted: 09/06/2013) - The immune system is normally known for protecting the body from illness. But a subset of immune cells appear to be doing more harm than good. A new study from researchers at the University of Michigan Comprehensive Cancer Center found that these cells, called myeloid derived suppressor cells, provide a niche where the cancer stem cells survive.

NCI clinician-scientists at the forefront of new prostate cancer diagnostics and treatment
NCI Feature Article
(Posted: 09/05/2013) - Introduction of the UroNav was the result of nearly a decade’s research and development, principally conducted at NCI. Resembling a stylized computer workstation on wheels, the system electronically fuses together pictures from magnetic resonance imaging and ultrasound to create a detailed, three-dimensional view of the prostate, which physicians can then use to guide precision biopsies.

Swallowing exercises shown to preserve function in head and neck cancer patients receiving radiation
NCI Cancer Center News
(Posted: 09/04/2013) - A study from UCLA’s Jonsson Comprehensive Cancer Center (JCCC) has found that head and neck cancer patients receiving radiation as part of their treatment were less likely to suffer unwanted side effects such as worsening of diet, need for a feeding tube, or narrowing of the throat passage if they complied with a set of prescribed swallowing exercises called a swallow preservation protocol (SPP) during therapy.

Inflammatory protein converts glioblastoma cells into most aggressive version
NCI Cancer Center News
(Posted: 08/30/2013) - A prominent protein activated by inflammation is the key instigator that converts glioblastoma multiforme cells to their most aggressive, untreatable form and promotes resistance to radiation therapy, an international team led by researchers at The University of Texas MD Anderson Cancer Center reported online in the journal Cancer Cell. The discovery by scientists and physicians points to new ways to increase radiation effectiveness and potentially block or reverse progression of glioblastoma multiforme, the most common and lethal form of brain tumor.

African-American women less likely to receive HPV vaccine than whites, even with access to health care
NCI Cancer Center News
(Posted: 08/30/2013) - Even with access to health care, African-American women are less likely to receive the vaccine for human papillomavirus (HPV), which reduces the risk for cervical cancer, according to a study by researchers at the University of Pittsburgh School of Medicine (home of the University of Pittsburgh Cancer Institute). The findings, published in the Journal of Adolescent Health, suggest a need for health care providers to both bolster HPV vaccination recommendations and address negative attitudes toward the vaccine among this vulnerable patient population.

School-age drinking increases breast cancer risk​​​​​​ according to Washington University study
NCI Cancer Center News
(Posted: 08/29/2013) - The more alcohol women drink before motherhood, the greater their risk of future breast cancer. That’s according to new research from Washington University School of Medicine in St. Louis that, for the first time, links increased breast cancer risk to drinking between early adolescence and first full-term pregnancy. Previous studies have looked at breast cancer risk and alcohol consumption later in life or at the effect of adolescent drinking on noncancerous breast disease.

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