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Hopkins researchers find that if prepped by tumor cells, lymphatic cells can encourage breast cancer cells to spread
NCI Cancer Center News
(Posted: 09/03/2014) - Breast cancer cells can lay the groundwork for their own spread throughout the body by coaxing cells within lymphatic vessels to send out tumor-welcoming signals.

Stanford researchers find that breast cancer patients with bilateral mastectomy don’t have better survival rates
NCI Cancer Center News
(Posted: 09/03/2014) - The first-ever direct comparison of breast cancer surgeries shows no survival benefit for women who had both breasts removed compared with women who underwent lumpectomy followed by radiation therapy.

Rutgers research reveals mechanism behind cell protein remodeling
NCI Cancer Center News
(Posted: 09/02/2014) - Researchers have demonstrated a concept that comes into play in remodeling proteins found within a family of cancers that does not respond well to cancer-treating drugs -- cancers driven by what is known as activated Ras.

Risk factors identified for certain lymphoma subtypes
NCI News Note
(Posted: 09/02/2014) - In a large international collaborative analysis of risk factors for non-Hodgkin lymphoma (NHL), scientists were able to quantify risk associated with medical history, lifestyle factors, family history of blood or lymph-borne cancers, and occupation for 11 different NHL subtypes, including less common subtypes.

Mass General researchers find that circulating tumor cell clusters are more likely to cause metastasis than single cells
NCI Cancer Center News
(Posted: 08/29/2014) - Tumor cells that break off a primary tumor and are carried through the bloodstream appear to be much more likely to cause metastasis than are single circulating tumor cells, according to a study from investigators at the Massachusetts General Hospital Cancer Center.

UC Davis researchers find that nanoparticles could provide applications to diagnose, treat cancer
NCI Cancer Center News
(Posted: 08/27/2014) - Researchers have created dynamic nanoparticles that could provide an arsenal of applications to diagnose and treat cancer.

Hopkins researchers find that cancer leaves a common fingerprint on DNA
NCI Cancer Center News
(Posted: 08/27/2014) - In a study of a broad variety of cancers, investigators say they have found widespread and distinctive changes to chemical marks known as methyl groups attached to DNA. Those marks help govern whether genes are turned “on” or “off,” and ultimately how the cell behaves.

In a study in nematode worms, Duke scientists uncover potential navigation system used by cancer, nerve cells
NCI Cancer Center News
(Posted: 08/26/2014) - Using nemotode worms, Duke University researchers have found a ”roving detection system” on the surface of cells that may point to new ways of treating diseases like cancer, Parkinson's disease and amyotrophic lateral sclerosis.

Northwestern researchers identify marker in aggressive breast cancer
NCI Cancer Center News
(Posted: 08/25/2014) - Two Northwestern University scientists have identified a biomarker strongly associated with basal-like breast cancer, a highly aggressive carcinoma that is resistant to many types of chemotherapy.

UCSD researchers report on new mouse model that points to therapy for liver disease
NCI Cancer Center News
(Posted: 08/22/2014) - Development of effective new therapies for preventing or treating non-alcoholic fatty liver disease has been stymied by limited small animal models for the disease. In a paper published online in Cancer Cell, scientists at the University of California, San Diego School of Medicine describe a novel mouse model that closely resembles human NASH and use it to demonstrate that interference with a key inflammatory protein inhibits both the development of NASH and its progression to liver cancer.

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