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Stanford researchers state that Big Bang model of colon cancer identifies role time plays in tumor-growth dynamics
Cancer Center News
(Posted: 02/11/2015) - A new model describing how colon tumors grow emphasizes the importance of time and the early origin of differences within and among tumors.

U Chicago researchers describe new screening tool that could speed development of ovarian cancer drugs
Cancer Center News
(Posted: 02/11/2015) - University of Chicago Medicine researchers have built a model system that uses multiple cell types from patients to rapidly test compounds that could block the early steps in ovarian cancer metastasis.

Brigham and Women's researchers discuss one-two punch that catches cancer cells in vulnerable state
Cancer Center News
(Posted: 02/11/2015) - By hitting breast cancer cells with a targeted therapeutic immediately after chemotherapy, researchers from Brigham and Women's Hospital were able to target cancer cells during a transitional stage when they were most vulnerable, killing cells and shrinking tumors in the lab and in pre-clinical models.

MD Anderson study identifies 8 signs associated with impending death in cancer patients
Cancer Center News
(Posted: 02/10/2015) - Researchers at The University of Texas MD Anderson Cancer Center have identified eight highly specific physical and cognitive signs associated with imminent death in cancer patients.

MD Anderson researchers find that cancer's ability to hijack regulatory mechanism increases metastasis
Cancer Center News
(Posted: 02/10/2015) - Some cancers grow using a biological matrix from which the tumor can thrive and spread.

UCSF-led study shows why some targeted cancer drugs lose effectiveness
Cancer Center News
(Posted: 02/10/2015) - A protein called YAP, which drives the growth of organs during development and regulates their size in adulthood, plays a key role in the emergence of resistance to targeted cancer therapies.

St. Jude researchers find that an inherited gene variation is tied to treatment-related hearing loss in cancer patients
Cancer Center News
(Posted: 02/10/2015) - St. Jude Children’s Research Hospital scientists have identified inherited genetic variations associated with hearing loss in young cancer patients treated with cisplatin, a drug widely used to treat adults with cancer.

Donor telomere length and survival after hematopoietic cell transplantation in patients with severe aplastic anemia
NCI News Note
(Posted: 02/10/2015) - A new NCI study has found that, among patients with severe aplastic anemia who received a hematopoietic cell transplant from an unrelated donor, those whose donor white blood cells had longer telomeres had higher survival rates five-years after transplantation than those whose donor white blood cells had shorter telomeres.

Sanford-Burnham study sheds light on cancer stem cell regulation
Cancer Center News
(Posted: 02/09/2015) - Researchers identify signaling molecules in intestinal stem cells that can lead to tumors if left unregulated. The findings suggest a new approach to targeting intestinal cancers.

Study Shows Elevated Number of Cancers in US HIV Positive Population
NCI News Note
(Posted: 02/09/2015) - In 2010, an estimated 7,760 new cancers were diagnosed among the nearly 900,000 Americans known to be living with HIV infection. According to the first comprehensive study in the United States, approximately half of these cancers were in excess of what would be expected if HIV-infected people had the same cancer risk as the general population.

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