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Dana-Farber study finds that oncologists differ widely on offering cancer gene testing
NCI Cancer Center News
(Posted: 03/25/2014) - A study by researchers at Dana-Farber Cancer Institute shows that not all doctors are ready to embrace tests that look for hundreds of DNA changes in patients' tumor samples, while others plan to offer this type of cancer gene testing to most of their patients.

UTSW researchers find that inherited mutated gene raises lung cancer risk for women, those who never smoked
NCI Cancer Center News
(Posted: 03/25/2014) - People who have an inherited mutation of a certain gene have a high chance of getting lung cancer — higher, even, than heavy smokers with or without the inherited mutation, according to new findings by cancer researchers at UT Southwestern Medical Center.

University of Chicago study reveals a major mechanism driving kidney cancer progression
NCI Cancer Center News
(Posted: 03/24/2014) - The shortage of oxygen, or hypoxia, created when rapidly multiplying kidney cancer cells outgrow their local blood supply can accelerate tumor growth by causing a nuclear protein called SPOP -- which normally suppresses tumor growth -- to move out of the nucleus to the cytoplasm, where it has the opposite effect, promoting rapid proliferation.

UNC study shows genetic, non-invasive test could improve colon cancer screening
NCI Cancer Center News
(Posted: 03/20/2014) - A non-invasive test that includes detection of the genetic abnormalities related to cancer could significantly improve the effectiveness of colon cancer screening, according to research from the UNC School of Medicine and UNC Lineberger Comprehensive Cancer Center.

Implementation of the NCI’s National Clinical Trials Network
NCI Perspective Article
(Posted: 03/20/2014) - NCI is launching a new clinical trials research network intended to improve treatment for the more than 1.6 million Americans diagnosed with cancer each year. The new system, NCI’s National Clinical Trials Network (NCTN), will facilitate the rapid initiation and completion of cancer clinical trials at over 3,000 clinical trials sites.
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Case Western researchers use big data to identify triple-negative breast, oropharyngeal, and lung cancers
NCI Cancer Center News
(Posted: 03/19/2014) - Researchers at Case Western Reserve University and colleagues used big data analytics to predict if a patient is suffering from aggressive triple-negative breast cancer, slower-moving cancers or non-cancerous lesions with 95 percent accuracy.

St. Jude researchers find that health gap between adult survivors of childhood cancer and siblings widens with age
NCI Cancer Center News
(Posted: 03/18/2014) - Long-term follow-up of adult survivors of childhood cancer reinforces need for lifelong health surveillance for childhood cancer survivors.

Dartmouth researchers develop approach to chronic lymphocytic leukemia treatment
NCI Cancer Center News
(Posted: 03/17/2014) - Dartmouth researchers have developed a different approach to treating Chronic Lymphocytic Leukemia (CLL), a form of blood cancer that often requires repeated chemotherapy treatments to which it grows resistant.

Dana-Farber study of genomic testing links 'exceptional' drug response to rare mutations in bladder cancer
NCI Cancer Center News
(Posted: 03/13/2014) - A patient with advanced bladder cancer, who was part of a phase 1 clinical trial, had a complete response for 14 months to a combination of the targeted drugs everolimus and pazopanib.

Stanford study finds that whole-genome sequencing for clinical use faces many challenges
NCI Cancer Center News
(Posted: 03/12/2014) - Whole-genome sequencing is a powerful technology, but a new Stanford study shows that significant challenges must be overcome before it can be routinely clinically useful.

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