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UCLA scientists discover how adult stem cell regulation contributes to lung cancer
NCI Cancer Center News
(Posted: 06/20/2014) - Stem cells that repair injuries in lung airways are regulated by molecules called reactive oxygen species (ROS). Increase in ROS levels trigger stem cells to divide and repair the airways; ROS then returns to the healthy baseline level.

Dana-Farber scientists identify additional challenges in KRAS-driven cancers
NCI Cancer Center News
(Posted: 06/20/2014) - Scientists have redoubled efforts to disable the mutated cancer gene KRAS, which confers an especially poor prognosis and has proved extraordinarily difficult to target.

Hopkins researchers find that a vaccine can reprogram pancreatic cancers to respond to immunotherapy
NCI Cancer Center News
(Posted: 06/19/2014) - Researchers at the Johns Hopkins Kimmel Cancer Center have developed and tested a vaccine that triggered the growth of immune cell nodules within pancreatic tumors, essentially reprogramming these intractable cancers and potentially making them vulnerable to immune-based therapies.

Study finds stronger nicotine dependency associated with higher risk of lung cancer
NCI News Note
(Posted: 06/19/2014) - NCI headed study finds people who are highly addicted to nicotine -- those who smoke their first cigarette within five minutes after awakening -- are at higher risk of developing lung cancer than those who wait for an hour or more to smoke.

Memorial Sloan-Kettering study compares survival for treatments of uncommon eye cancer
NCI Cancer Center News
(Posted: 06/18/2014) - In patients with advanced uveal melanoma, treatment with the agent selumetinib, compared with chemotherapy, resulted in an improved cancer progression-free survival time and tumor response rate, but no improvement in overall survival, according to a study in the June 18 issue of JAMA.

Duke scientists find that heparin derivative suppresses neuroblastoma tumor growth
NCI Cancer Center News
(Posted: 06/18/2014) - Researchers at Duke Medicine have identified a new strategy for treating neuroblastoma using a modified version of heparin, a century-old injectable drug that thins the blood to prevent clots from forming.

Duke researchers find that combining treatments boosts some smokers’ ability to quit
NCI Cancer Center News
(Posted: 06/18/2014) - Combining two smoking cessation therapies is more effective than using just one for male and highly nicotine-dependent smokers who weren't initially helped by the nicotine patch, according to researchers at Duke Medicine.

NIH and NSF collaborate to accelerate biomedical research innovations into the marketplace
NIH/NSF Press Release
(Posted: 06/18/2014) - A collaboration between the National Science Foundation and the National Institutes of Health will give NIH-funded researchers training to help them evaluate their scientific discoveries for commercial potential, with the aim of accelerating biomedical innovations into applied health technologies.

Lung-MAP Launches: First Precision Medicine Trial From National Clinical Trials Network
NCI Press Release
(Posted: 06/16/2014) - A unique public-private collaboration today announced the initiation of the Lung Cancer Master Protocol (Lung-MAP) trial, a multi-drug, multi-arm, biomarker-driven clinical trial for patients with advanced squamous cell lung cancer.
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Harvard and Broad Institute researchers chart cellular complexity of brain tumors
NCI Cancer Center News
(Posted: 06/13/2014) - By examining the gene expression patterns of many individual cells, one at a time, a research team was able to get a finer picture of the cellular composition of gliobastoma.

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