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Hopkins researchers find that cell's recycling center is implicated in division decisions
NCI Cancer Center News
(Posted: 07/29/2014) - Researchers at The Johns Hopkins University have identified a mechanism that overrides a cells’ warning signals, enabling cancers to continue to divide even without a robust blood supply.

Huntsman researchers discovery of protein's role in making platelets in mice may aid multiple myeloma patients
NCI Cancer Center News
(Posted: 07/28/2014) - A University of Utah School of Medicine-led study in mice has identified a previously unknown but crucial component in the process to make platelets, a discovery that could help spare multiple myeloma patients from a dangerous side effect of the primary drug (bortezomib) used to treat their cancer.

Baylor mouse study shows epigenetic changes can drive cancer
NCI Cancer Center News
(Posted: 07/28/2014) - Researchers at the USDA/ARS Children’s Nutrition Research Center at Baylor College of Medicine and Texas Children’s Hospital have now created a mouse model providing the first in vivo evidence that epigenetic alterations alone can cause cancer.

Vanderbilt-led study identifies genes linked to breast cancer in East Asian women
NCI Cancer Center News
(Posted: 07/24/2014) - A new study in East Asian women has identified three genetic changes linked to an increased risk of breast cancer.

TCGA researchers identify four subtypes of stomach cancer
NCI Press Release
(Posted: 07/23/2014) - Stomach cancers fall into four distinct molecular subtypes, researchers with The Cancer Genome Atlas (TCGA) Network have found. Scientists report that this discovery could change how researchers think about developing treatments for stomach cancer, also called gastric cancers or gastric adenocarcinomas.

Penn Medicine researchers find that a metabolic enzyme stops progression of most common type of kidney cancer
NCI Cancer Center News
(Posted: 07/21/2014) - Researchers found that an enzyme called FBP1 -- essential for regulating metabolism -- binds to a transcription factor in the nucleus of certain kidney cells and restrains energy production in the cell body.

Researchers report first large-scale integrated proteomic and genomic analysis of a human cancer: Identification of new molecular features of colorectal cancer
NCI News Note
(Posted: 07/21/2014) - Investigators who analyzed 95 human colorectal tumor samples have determined how gene alterations identified in previous analyses of the same samples are expressed at the protein level. The integration of proteomic and genomic data, or proteogenomics, provides a more comprehensive view of the biological features that drive cancer than genomic analysis alone.

Salk scientists identify a new gene that could stop the spread of deadly cancer
NCI Cancer Center News
(Posted: 07/18/2014) - Scientists at the Salk Institute have identified a gene responsible for stopping the movement of cancer from the lungs to other parts of the body, indicating a new way to fight one of the world's deadliest cancers.

NIH study finds negative HPV screening test result is a better predictor of low cervical cancer risk than a negative Pap test
NCI Press Release
(Posted: 07/18/2014) - Based on a study that included more than 1 million women, investigators at NCI have determined that a negative test for HPV infection compared to a negative Pap test provides greater safety, or assurance, against future risk of cervical cancer.
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Multi-institute research on prostate cancer is focus of 2 studies, commentary
NCI Cancer Center News
(Posted: 07/15/2014) - Management of low-risk prostate cancer varies widely among urologists and radiation oncologists, with patients whose diagnosis is made by a urologist that treats non-low-risk prostate cancer more likely to receive treatment vs. observation.

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