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Sanford-Burnham study sheds light on cancer stem cell regulation
Cancer Center News
(Posted: 02/09/2015) - Researchers identify signaling molecules in intestinal stem cells that can lead to tumors if left unregulated. The findings suggest a new approach to targeting intestinal cancers.

Study Shows Elevated Number of Cancers in US HIV Positive Population
NCI News Note
(Posted: 02/09/2015) - In 2010, an estimated 7,760 new cancers were diagnosed among the nearly 900,000 Americans known to be living with HIV infection. According to the first comprehensive study in the United States, approximately half of these cancers were in excess of what would be expected if HIV-infected people had the same cancer risk as the general population.

Hopkins researchers find that cell signaling pathway goes awry in common pediatric brain tumor
Cancer Center News
(Posted: 02/06/2015) - A new study by Johns Hopkins researchers links a well-known cell communication pathway called Notch to one of the most common -- but overall still rare -- brain tumors found in children.

Hopkins scientists find that in rats new nanoparticle gene therapy strategy effectively treats deadly brain cancer
Cancer Center News
(Posted: 02/05/2015) - Researchers have used nanoparticles to deliver a new therapy to glioma cells in the brains of rats, prolonging their lives.

UNC researchers note that pancreatic cancer treatment might increase life expectancy
Cancer Center News
(Posted: 02/05/2015) - Device that drives drugs into solid tumors that are poorly vascularized opens the possibility of life-saving surgeries in cancer patients

Mayo Clinic study finds that ultrasound narrows down which breast cancer patients need lymph nodes removed
NCI Cancer Center News
(Posted: 02/03/2015) - Which breast cancer patients need to have underarm lymph nodes removed? Mayo Clinic-led research is narrowing it down.

Roswell Park analysis of key breast cancer genes reveals distinct profiles for African-American, European-American women
NCI Cancer Center News
(Posted: 01/29/2015) - Researchers have uncovered new information that may begin to explain why many African-American women are more likely to be diagnosed with aggressive, often deadly forms of breast cancer.

NIH-funded study uncovers range of molecular alterations in head and neck cancers, new potential drug targets; TCGA tumor genome sequencing analyses offer new insights into the effects of HPV and smoking
NCI Press Release
(Posted: 01/28/2015) - Investigators with The Cancer Genome Atlas (TCGA) Research Network have discovered genomic differences – with potentially important clinical implications – in head and neck cancers caused by infection with the human papillomavirus (HPV).

Mayo Clinic researchers report that a new breast cancer risk prediction model may be more accurate than current model
NCI Cancer Center News
(Posted: 01/27/2015) - A new breast cancer risk prediction model combining histologic features of biopsied breast tissue from women with benign breast disease and individual patient demographic information more accurately classified breast cancer risk than the current screening standard.

St. Jude researchers find that an inherited gene variation helps explain drug toxicity in patients of East Asian ancestry
NCI Cancer Center News
(Posted: 01/27/2015) - St. Jude researchers have identified an inherited variation in the NUDT15 gene that is strongly associated with a low tolerance for a drug that is a mainstay of pediatric ALL treatment.

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