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UPenn researchers find that blocking autophagy with malaria drug may help overcome resistance to melanoma BRAF drugs
NCI Cancer Center News
(Posted: 02/25/2014) - A new preclinical study published in the Journal of Clinical Investigation found that the root of BRAF drug resistance may lie in a never-before-seen autophagy mechanism induced by the BRAF inhibitors vermurafenib and dabrafenib.

Mouse study identifies enzyme with key role in precancerous lesions
NCI Cancer Center News
(Posted: 02/24/2014) - In a new study, researchers led by a molecular biologist at the University of California, San Francisco report two breakthroughs in understanding those lesions and their role in pancreatic cancer.

NCI supported study of selenium and vitamin E supplements shows an increase risk of prostate cancer in some men
NCI Cancer Center News
(Posted: 02/24/2014) - Supplementation with both the trace element selenium and vitamin E increase the risk of high-grade prostate cancer.

UCLA scientisits find that tissue-penetrating light releases chemotherapy inside cancer cells
NCI Cancer Center News
(Posted: 02/21/2014) - Dr. Jeffrey Zink Dr. Fuyu Tamanoi Researchers from the cancer nanotechnology and signal transduction and therapeutics programs of UCLA’s Jonsson Comprehensive Cancer Center have developed a technique using light to carry chemotherapy to cancer cells.

University of Arizona researchers report on cervical cancer study
NCI Cancer Center News
(Posted: 02/21/2014) - Dr. Monk is nationally recognized for his expertise in cervical cancer and chairs the Gynecologic Oncology Cervical Cancer Committee for the National Cancer Institute funded Gynecologic Oncology Group for the study published in NEJM.

St. Jude gene sequencing project discovers common driver of a childhood brain tumor
NCI Cancer Center News
(Posted: 02/20/2014) - St. Jude Children’s Research Hospital -Washington University Pediatric Cancer Genome Project identifies the most common genetic alteration yet in the brain tumor ependymoma; results offer clues for fighting other cancers.

Memorial Sloan-Kettering researchers find that cell therapy shows ability to eradicate cancer in clinical study
NCI Cancer Center News
(Posted: 02/20/2014) - A large clinical study... of patients with advanced leukemia found that 88 percent achieved complete remissions after being treated with genetically modified versions of their own immune cells.

Ohio State researchers find that addition of bevacizumab to the treatment of newly diagnosed brain tumors does not extend patients’ lives
NCI Cancer Center News
(Posted: 02/20/2014) - Results from a randomized, phase 3 clinical trial conducted by the RTOG have shown that adding bevacizumab to the treatment of glioblastoma does not improve patient survival.

NIH study confirms risk factors for male breast cancer
NCI News Note
(Posted: 02/19/2014) - Pooled data from studies of about 2,400 men with breast cancer and 52,000 men without breast cancer confirmed that risk factors for male breast cancer include obesity, a rare genetic condition called Klinefelter syndrome, and gynecomastia.

Stanford study highlights technique that allows for radiation-free detection of tumors
NCI Cancer Center News
(Posted: 02/19/2014) - Researchers have developed a way to scan young cancer patients' bodies for tumors without exposing them to radiation, which could reduce their risk of developing secondary cancers.

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