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Volume 6, Issue 4
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Audio
TRANSCRIPT: Dr. Claudia Baquet, M.D., discusses aspects of minority enrollment in clinical trials such as the Selenium and Vitamin E Cancer Prevention Trial, a clinical trial to see if one or both dietary supplement can reduce the risk of prostate cancer in high risk patients such as African American males.
For example, in the SELECT trial [the Selenium and Vitamin E Cancer Prevention Trial, a clinical trial to see if one or both dietary supplement can reduce the risk of prostate cancer in high risk patients such as African American males. While national accrual to this study went well, patients who had uncontrolled hypertension were not eligible and were excluded. Well, some of the communities that are at most risk for higher incidence for prostate cancer also have a higher prevalence of hypertension. So minority populations can be restricted from clinical trials just because of how the trial is designed and eligibility criteria developed. Other conditions that may preclude people from participating in trials include diabetes, peripheral arterial disease, and chronic pulmonary disease. It depends on the trial design and criteria. |
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