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NCI Cancer Center News

Study identifies anti-aging gene as tumor suppressor in mice

  • Posted: December 12, 2012

A new study sheds more light on how an anti-aging gene suppresses cancer growth, joint University of Michigan Health System (home to the University of Michigan Comprehensive Cancer Center) and Harvard Medical School (home to the Dana-Farber Cancer Institute) research shows. Loss of the SIRT6 protein in mice increases the number, size and aggressiveness of tumors, according to the new research published in the scientific journal Cell. The study also suggests that the loss of SIRT6 promotes tumor growth in human colon and pancreatic cancers.

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NCI comprehensive cancer centers logoAmong the research institutions NCI funds across the United States, it currently designates 67 as Cancer Centers. Largely based in research universities, these facilities are home to many of the NCI-supported scientists who conduct a wide range of intense, laboratory research into cancer’s origins and development. The Cancer Centers Program also focuses on trans-disciplinary research, including population science and clinical research. The centers’ research results are often at the forefront of studies in the cancer field.