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NCI Cancer Center News

UNC study finds B cell survival holds key to chronic graft vs. host disease

  • Posted: August 17, 2012

In a paper published online August 15 by the journal, Blood, a team from the University of North Carolina’s Lineberger Comprehensive Cancer Center, shows in the laboratory that B cells from patients with chronic Graft vs. Host Disease are much more active than cells from patients without the disease.  The team also outlines the cell signaling pathways that contribute to this increased activity – identifying a promising target for developing new therapies for the diseases.

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