UNC study finds B cell survival holds key to chronic graft vs. host disease
In a paper published online August 15 by the journal, Blood, a team from the University of North Carolina’s Lineberger Comprehensive Cancer Center, shows in the laboratory that B cells from patients with chronic Graft vs. Host Disease are much more active than cells from patients without the disease. The team also outlines the cell signaling pathways that contribute to this increased activity – identifying a promising target for developing new therapies for the diseases.
Among the research institutions NCI funds across the United States, it currently designates 67 as Cancer Centers. Largely based in research universities, these facilities are home to many of the NCI-supported scientists who conduct a wide range of intense, laboratory research into cancer’s origins and development. The Cancer Centers Program also focuses on trans-disciplinary research, including population science and clinical research. The centers’ research results are often at the forefront of studies in the cancer field.