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  • Posted: 12/17/2012

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NCI Cancer Center News

Brigham and Women's Researchers Find That Low Adiponcetin Is Associated With Increased Pancreatic Cancer Risk

Low prediagnostic levels of circulating adiponectin were associated with an increased risk of pancreatic cancer... Pancreatic cancer is the fourth leading cause of cancer death in the U.S., but its etiology remains unclear. Adiponectin, a hormone secreted from fat cells, has insulin-sensitizing and anti-inflammatory properties. Low adiponectin plasma levels are associated with the insulin resistance that manifests in obesity and diabetes mellitus, both of which are risk factors for pancreatic cancer.

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Among the research institutions NCI funds across the United States, it currently designates 67 as Cancer Centers. Largely based in research universities, these facilities are home to many of the NCI-supported scientists who conduct a wide range of intense, laboratory research into cancer’s origins and development. The Cancer Centers Program also focuses on trans-disciplinary research, including population science and clinical research. The centers’ research results are often at the forefront of studies in the cancer field.