USC study finds epidermal growth factor inhibits colitis-associated cancer

Epidermal growth factor (EGF) is a protein that normally regulates intestinal healing. However, biological therapies such as EGF also may pose the risk of increasing the possibility of cancer. In a paper published online in The Journal of Clinical Investigation, USC investigators reported that EGF encourages healing and provides powerful anti-inflammatory properties. Together, these functions actually prevent inflammation-induced cancer, superseding any potential tumor-promoting role. USC is home to the Norris Comprehensive Cancer Center.

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Among the research institutions NCI funds across the United States, it currently designates 66 as Cancer Centers. Largely based in research universities, these facilities are home to many of the NCI-supported scientists who conduct a wide range of intense, laboratory research into cancer’s origins and development. The Cancer Centers Program also focuses on trans-disciplinary research, including population science and clinical research. The centers’ research results are often at the forefront of studies in the cancer field.