Albert Einstein researchers' gene discovery could improve treatment for acute myeloid leukemia
Scientists at Albert Einstein College of Medicine of Yeshiva University have discovered, in a mouse model of acute myeloid leukemia, that the gene HLX is expressed at abnormally high levels in leukemia stem cells. Gene expression is the process by which a gene synthesizes the molecule that it codes for; an "over-expressed" gene makes its product in abnormally high amounts. These findings suggest that targeting elevated HLX expression may be a promising novel strategy for treating AML. The Albert Einstein College of Medicine is home to the Albert Einstein Cancer Center.
Among the research institutions NCI funds across the United States, it currently designates 67 as Cancer Centers. Largely based in research universities, these facilities are home to many of the NCI-supported scientists who conduct a wide range of intense, laboratory research into cancer’s origins and development. The Cancer Centers Program also focuses on trans-disciplinary research, including population science and clinical research. The centers’ research results are often at the forefront of studies in the cancer field.