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NCI Cancer Center News

Gene sequencing project identifies abnormal gene that launches rare childhood leukemia

  • Posted: November 13, 2012

Research led by the St. Jude Children’s Research Hospital – Washington University Pediatric Cancer Genome Project has identified a fusion gene responsible for almost 30 percent of a rare subtype of childhood leukemia with an extremely poor prognosis. The finding offers the first evidence of a mistake that gives rise to a significant percentage of acute megakaryoblastic leukemia (AMKL) cases in children. AMKL accounts for about 10 percent of pediatric acute myeloid leukemia (AML). The discovery paves the way for desperately needed treatment advances.

Click here to read full press release from St. Jude Children's Research Hospital.

Click here to read full press release from Washington University in St. Louis.

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