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NCI Cancer Center News

UCSF researchers and others identify therapeutic targets in neurofibromatosis

  • Posted: December 11, 2012

In the current issue of the Journal of Clinical Investigation, three independent groups of researchers, including those from UCSF, report that MAPK hyperactivation is a critical mediator of disease pathogenesis in neurofibromatosis.

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Among the research institutions NCI funds across the United States, it currently designates 67 as Cancer Centers. Largely based in research universities, these facilities are home to many of the NCI-supported scientists who conduct a wide range of intense, laboratory research into cancer’s origins and development. The Cancer Centers Program also focuses on trans-disciplinary research, including population science and clinical research. The centers’ research results are often at the forefront of studies in the cancer field.