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  • Posted: 02/07/2013

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NCI Cancer Center News

University of Minnesota researchers discover enzyme behind breast cancer mutations

Researchers at the University of Minnesota and its Masonic Cancer Center have uncovered a human enzyme responsible for causing DNA mutations found in the majority of breast cancers. The discovery of this enzyme – called APOBEC3B – may change the way breast cancer is diagnosed and treated.

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NCI comprehensive cancer centers logo

Among the research institutions NCI funds across the United States, it currently designates 67 as Cancer Centers. Largely based in research universities, these facilities are home to many of the NCI-supported scientists who conduct a wide range of intense, laboratory research into cancer’s origins and development. The Cancer Centers Program also focuses on trans-disciplinary research, including population science and clinical research. The centers’ research results are often at the forefront of studies in the cancer field.