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NCI Cancer Center News

Inflammatory protein converts glioblastoma cells into most aggressive version

  • Posted: August 30, 2013

A prominent protein activated by inflammation is the key instigator that converts glioblastoma multiforme cells to their most aggressive, untreatable form and promotes resistance to radiation therapy, an international team led by researchers at The University of Texas MD Anderson Cancer Center reported online in the journal Cancer Cell. The discovery by scientists and physicians points to new ways to increase radiation effectiveness and potentially block or reverse  progression of glioblastoma multiforme, the most common and lethal form of brain tumor.

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NCI comprehensive cancer centers logoAmong the research institutions NCI funds across the United States, it currently designates 68 as Cancer Centers. Largely based in research universities, these facilities are home to many of the NCI-supported scientists who conduct a wide range of intense, laboratory research into cancer’s origins and development. The Cancer Centers Program also focuses on trans-disciplinary research, including population science and clinical research. The centers’ research results are often at the forefront of studies in the cancer field.