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NCI Cancer Center News

UCSD study illuminates how cells know when it’s time to eat themselves

  • Posted: January 18, 2013

Researchers at the University of California, San Diego School of Medicine and the Moores Comprehensive Cancer Center have identified a molecular mechanism regulating autophagy, a fundamental stress response used by cells to help ensure their survival in adverse conditions. The researchers report that an enzyme called AMPK, typically involved in sensing and modulating energy use in cells, also regulates autophagic enzymes. Failure of normal autophagy has been associated with accumulated cell damage and aging.

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