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  • Posted: 04/08/2013
NCI Cancer Center News

NCI Cancer Centers at AACR: 2013

The American Association for Cancer Research is the world’s foremost professional organization dedicated to the field of cancer research. With a membership of more than 34,000, representing over 90 countries, the AACR’s annual meeting draws thousands of  attendees to five days of intensive science presentations and educational sessions. Each year, the institutions that comprise the network of NCI-designated Cancer Centers are strong scientific presences. This year’s meeting in Washington, D.C., is no exception. Some highlights of the centers’ presentations at AACR are below. They will be updated throughout the meeting.

 

Saturday, April 6

Saturday’s first news conference, “Late Breaking Clinical Trials,” chaired by AACR President-elect Charles L. Sawyers, M.D., from the Memorial Sloan-Kettering Cancer Center, featured research from three institutions that are home to NCI-designated Cancer Centers:

 

Saturday’s second news conference, “Genomics and Predictors of Outcomes,” chaired by Giuseppe Giaccone, M.D., Ph.D., from the Georgetown Lombardi Comprehensive Cancer Center, featured research from three institutions that are home to NCI-designated Cancer Centers:

 

Sunday, April 7

Sunday’s plenary session, “From Discovery Science to Precision Medicine: Paving the Path to Progress,” was chaired by José Baselga, M.D., Ph.D., from the Memorial Sloan-Kettering Cancer Center. Speakers affiliated with NCI-designated Cancer Centers were:

  • “From Genes to Microenvironments: Cancer as an ‘Organismal’ Disease”: Siddharta Mukherjee, M.D., Ph.D., Columbia University (home to the Herbert Irving Comprehensive Cancer Center)
  • “Immune Checkpoint Blockade: Unleashing the Immune System Against Cancer”: Suzanne L. Topalian, M.D., Johns Hopkins Sidney Kimmel Comprehensive Cancer Center
  • “The Therapeutic Implications of Genome Sequencing and Expression Analyses for Breast Cancer”: Charles M. Perou, Ph.D., University of North Carolina Lineberger Comprehensive Cancer Center

 

Sunday’s news conference, “Treatment and Resistance to Targeted Therapies,” chaired by Levi Garraway, M.D., Ph.D., from the Dana-Farber Cancer Institute, featured research from one NCI-designated Cancer Center:

 

On Sunday, AACR issued four news releases featuring research from institutions that are home to NCI-designated Cancer Centers:

  • “Novel Serum Biomarker Bilirubin Predicted Lung Cancer Risk in Smokers”: Xifeng Wu, M.D., Ph.D., University of Texas MD Anderson Cancer Center
  • “KDM1 May Represent a New Therapeutic Target for Glioma”: Gangadhara R. Sareddy, Ph.D., University of Texas Health Science Center in San Antonio (home to the Cancer Therapy & Research Center
  • “Older Women Who Delay Mammography Screening More Likely to Die From Breast Cancer”: Michael S. Simon, M.D., M.P.H., Barbara Ann Karmanos Cancer Institute
  • “Next-generation PI3 Kinase Inhibitor Demonstrated Early Efficacy, Safety”: Dejan Juric, M.D., Massachusetts General Hospital (affiliate of the Dana-Farber Cancer Institute

 

Monday, April 8

Monday’s plenary session was “Epigenetic Targets for Cancer.” Speakers affiliated with NCI-designated Cancer Centers were:

  • “Cancer Genetic and Epigenetic Interactions”: Peter W. Laird, Ph.D., University of Southern California Norris Comprehensive Cancer Center
  • “Bromodomain Inhibition in Cancer”: James E. Bradner, M.D., Dana-Farber Cancer Institute

 

On Monday, AACR issued three news releases featuring research from institutions that are home to NCI-designated Cancer Centers:

  • “Some Melanoma Survivors Still Use Tanning Beds, Skip Sunscreen”: Anees B. Chagpar, M.D., M.P.H., Yale School of Medicine (home to the Yale Cancer Center)
  • “Novel AKT Pathway Inhibitor, ARQ 092, Demonstrated Safety, Effective Target Inhibition”: Mansoor N. Saleh, M.D., University of Alabama Comprehensive Cancer Center in Birmingham
  • “Exposure to Air Pollution During Pregnancy Linked to Increased Incidence of Specific Pediatric Cancers”: Julia Heck, Ph.D., M.P.H., University of California, Los Angeles (home to the Jonsson Comprehensive Cancer Center)

 

Tuesday, April 9

On Tuesday, AACR issued a news release featuring research from an institution that is home to an NCI-designated Cancer Center:

  • “Prevalence of Benign Disease Diagnosis After Lung Surgery Varied Widely by State”: Stephen A. Deppen, doctoral candidate, Vanderbilt University (home to the Vanderbilt-Ingram Cancer Center)

 

Wednesday, April 10

Wednesday’s plenary session, “Cancer Evolution and Resistance,” was chaired by Jeffrey A. Engelman, M.D., Ph.D., from the Massachusetts General Hospital (an affiliate of the Dana-Farber Cancer Institute). Speakers affiliated with NCI-designated Cancer Centers were:

  • “Oncoprotein-induced Feedback and Adaptive resistance to Targeted Therapy”: Neal Rosen, M.D., Ph.D., Memorial Sloan-Kettering Cancer Center
  • “Microenvironmental Contributions to Cancer Drug Resistance”: Todd R. Golub, M.D., Broad Institute of MIT and Harvard, and the Dana-Farber Cancer Institute

 

On Wednesday, AACR issued two news releases featuring research from institutions that are home to NCI-designated Cancer Centers:

  • “High Calcium Intake Associated With Reduced Colorectal Adenoma Risk in Certain Individuals”: Xiangzhu Zhu, M.D., M.P.H., Vanderbilt-Ingram Cancer Center
  • “Biomarkers Discovered That May Help Predict Response to Drugs Targeting KRAS-mutated NSCLC”: Aaron N. Hata, M.D., Ph.D., Massachusetts General Hospital (an affiliate of the Dana-Farber Cancer Institute)