Protein protects against breast cancer recurrence in animal model
Precisely what causes breast cancer recurrence has been poorly understood. But now a piece of the puzzle has fallen into place: Researchers at the Perelman School of Medicine, University of Pennsylvania (home of the Abramson Cancer Center) have identified a key molecular player in recurrent breast cancer – a finding that suggests potential new therapeutic strategies. The study, performed in an animal model, implicates the tumor suppressor protein Par-4 in recurrent breast cancer.
Among the research institutions NCI funds across the United States, it currently designates 67 as Cancer Centers. Largely based in research universities, these facilities are home to many of the NCI-supported scientists who conduct a wide range of intense, laboratory research into cancer’s origins and development. The Cancer Centers Program also focuses on trans-disciplinary research, including population science and clinical research. The centers’ research results are often at the forefront of studies in the cancer field.