A novel surface marker helps scientists ‘fish out’ mammary gland stem cells
In a paper published in Proceedings of the National Academy of Sciences, scientists at Cold Spring Harbor Laboratory (CSHL) used a mouse model to identify a novel cell surface marker on mammary gland stem cells. Using that marker, the team was able to assemble a sample of mammary gland stem cells of unprecedented purity. Until now, isolating pure mammary gland stem cells, which are important in mammary gland development as well as breast cancer formation, has posed a challenge.
Among the research institutions NCI funds across the United States, it currently designates 67 as Cancer Centers. Largely based in research universities, these facilities are home to many of the NCI-supported scientists who conduct a wide range of intense, laboratory research into cancer’s origins and development. The Cancer Centers Program also focuses on trans-disciplinary research, including population science and clinical research. The centers’ research results are often at the forefront of studies in the cancer field.