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NCI Cancer Center News

Study uncovers secrets behind the process of some cancers

  • Posted: October 29, 2013

Researchers at Fox Chase Cancer Center have discovered new clues about how some genes are turned on and off inside a cell—a process that, when it goes awry, can lead to cancer. The new findings appear online in the October 24, 2013 edition of the journal Cell Reports. The researchers worked to uncover details about how a single protein is able to physically "silence" gene clusters. If certain “tumor suppressor genes” get inadvertently caught up in such silencing, they say, this may cause cells to divide uncontrollably and lead to cancer.

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NCI Comprehensive Cancer Centers logoAmong the research institutions NCI funds across the United States, it currently designates 68 as Cancer Centers. Largely based in research universities, these facilities are home to many of the NCI-supported scientists who conduct a wide range of intense, laboratory research into cancer’s origins and development. The Cancer Centers Program also focuses on trans-disciplinary research, including population science and clinical research. The centers’ research results are often at the forefront of studies in the cancer field.