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NCI Cancer Center News

UCSD scientists identify shape-shifting nanoparticles that flip from sphere to net in response to tumor signals

  • Posted: May 29, 2013

According to UCSD scientists, an enzyme produced by a specific type of tumor can trigger the transformation of spheres into netlike structures that accumulate at the site of a cancer... Spherical nanoparticles labeled with red or green dye shift their shapes and accumulate into netlike structures when they encounter a protease secreted by some kinds of cancerous tumors.

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Among the research institutions NCI funds across the United States, it currently designates 67 as Cancer Centers. Largely based in research universities, these facilities are home to many of the NCI-supported scientists who conduct a wide range of intense, laboratory research into cancer’s origins and development. The Cancer Centers Program also focuses on trans-disciplinary research, including population science and clinical research. The centers’ research results are often at the forefront of studies in the cancer field.