Harvard and Broad Institute researchers chart cellular complexity of brain tumors
Previous studies of glioblastoma looked at the average expression of genes across millions of cells, which were slurried together in a single sample. In some cases, this type of sampling is used to classify glioblastoma tumors into one of four recognized cancer sub-types, based on the gene expression program that is most prevalent. By examining the gene expression patterns of many individual cells, one at a time, the team was able to get a finer picture of the cellular composition of the tumors.
Among the research institutions NCI funds across the United States, it currently designates 68 as Cancer Centers. Largely based in research universities, these facilities are home to many of the NCI-supported scientists who conduct a wide range of intense, laboratory research into cancer’s origins and development. The Cancer Centers Program also focuses on trans-disciplinary research, including population science and clinical research. The centers’ research results are often at the forefront of studies in the cancer field.