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NCI Cancer Center News

Hopkins researchers find that blood and saliva tests help predict return of HPV-linked oral cancers

  • Posted: August 4, 2014

Johns Hopkins scientists have developed blood and saliva tests that help accurately predict recurrences of HPV-linked oral cancers in a substantial number of patients. The tests screen for DNA fragments of the human papillomavirus (HPV) shed from cancer cells lingering in the mouth or other parts of the body. The scientists found that HPV DNA detected in patients' saliva after treatment was predictive for recurrence nearly 20 percent of the time in a subset of the patients.

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NCI Comprehensive Cancer Center logoAmong the research institutions NCI funds across the United States, it currently designates 68 as Cancer Centers. Largely based in research universities, these facilities are home to many of the NCI-supported scientists who conduct a wide range of intense, laboratory research into cancer’s origins and development. The Cancer Centers Program also focuses on trans-disciplinary research, including population science and clinical research. The centers’ research results are often at the forefront of studies in the cancer field.