Huntsman researchers discovery of protein's role in making platelets in mice may aid multiple myeloma patients
A University of Utah School of Medicine-led study has identified a previously unknown but crucial component in the process to make platelets, a discovery that could help spare multiple myeloma patients from a dangerous side effect of the primary drug (bortezomib) used to treat their cancer. The researchers show that when the proteasome, which is a protein complex that breaks down the proteins that regulate cellular processes, is pharmaceutically inhibited platelet production in human and mice cells was blocked.
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Among the research institutions NCI funds across the United States, it currently designates 68 as Cancer Centers. Largely based in research universities, these facilities are home to many of the NCI-supported scientists who conduct a wide range of intense, laboratory research into cancer’s origins and development. The Cancer Centers Program also focuses on trans-disciplinary research, including population science and clinical research. The centers’ research results are often at the forefront of studies in the cancer field.