Researchers develop tool to determine individual risk of prostate cancer overdiagnosis
Researchers at Fred Hutchinson Cancer Research Center and the University of Washington have developed a personalized tool that can predict the likelihood of prostate cancer overdiagnosis. They announced their findings this week in the online issue of the Journal of the National Cancer Institute. The researchers created a nomogram, a graphical calculating device, that incorporates a patient’s age, prostate-specific antigen (PSA) level and Gleason score – which grades prostate cancer tissue based on how it looks under a microscope – to determine the likelihood that screening-detected prostate cancer has been overdiagnosed.
Among the research institutions NCI funds across the United States, it currently designates 68 as Cancer Centers. Largely based in research universities, these facilities are home to many of the NCI-supported scientists who conduct a wide range of intense, laboratory research into cancer’s origins and development. The Cancer Centers Program also focuses on trans-disciplinary research, including population science and clinical research. The centers’ research results are often at the forefront of studies in the cancer field.