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News from NCI

  • Image-guided biopsy for diagnosis of prostate cancer can increase detection of high-risk tumors
    NCI News Note

    (Posted: 01/27/2015) - In the largest prospective study to date of image-guided technology for identifying suspicious regions of the prostate to biopsy, researchers compared the ability of this technology to detect high-risk prostate cancer with that of the current standard of unguided prostate biopsy.

  • SDHC epimutant GIST with epithelioid morphology
    A key molecular defect in a childhood gastrointestinal tumor may have important diagnostic implications
    NCI News Note

    (Posted: 12/24/2014) - NCI scientists have identified a key molecular defect in a tumor in children known as gastrointestinal stromal tumor, or GIST, that may have important diagnostic implications.

  • More than 300 million people in at least 70 countries use smokeless tobacco
    NCI/CDC Press Release

    (Posted: 12/15/2014) - The first-ever report on the global use and public health impact of smokeless tobacco finds that more than 300 million people in at least 70 countries use these harmful products. The report is titled Smokeless Tobacco and Public Health: A Global Perspective.

  • A clinical trial sponsored and supported by NCI showed that suppressing ovarian function reduced breast cancer recurrence in premenopausal women receiving the drug tamoxifen after surgery for early-stage breast cancer.
    Premenopausal women who received ovarian suppression treatment along with tamoxifen had a lower risk of breast cancer recurrence
    NCI News Note

    (Posted: 12/11/2014) - A clinical trial sponsored and supported by NCI showed that suppressing ovarian function reduced breast cancer recurrence in premenopausal women receiving the drug tamoxifen after surgery for early-stage breast cancer.

  • Double-stranded DNA molecule inside the nucleus.
    NCI establishes Genomic Data Commons to facilitate identification of molecular subtypes of cancer and potential drug targets
    NCI News Note

    (Posted: 12/02/2014) - NCI is establishing the Genomic Data Commons to store, analyze and distribute cancer genomics data generated by NCI and other research organizations. The GDC will provide an interactive system for researchers to access data, with the goal of advancing the molecular diagnosis of cancer and suggest potential therapeutic targets based on genomic information.

  • A drawing of cells of the cervix, in purple, with a bottom epithelium layer of small round cells with large nuclei, a basal membrane, and a top layer of stroma, or connective tissue
    Multiple biopsies are superior to a single biopsy in detecting cervical cancer precursors
    NCI News Note

    (Posted: 11/24/2014) - Performing multiple biopsies during a procedure known as colposcopy—visual inspection of the cervix—is more effective than performing only a single biopsy of the worst-appearing area for detecting cervical cancer precursors. This multiple biopsy approach may help to detect disease early and avoid repeated biopsies for women with initial negative findings, according to a new study by researchers at the National Cancer Institute and their colleagues.

  • Small group of doctor team joining hands.
    Recipients of Cancer Clinical Investigator Team Leadership Awards Announced
    NCI News Note

    (Posted: 11/12/2014) - NCI’s Cancer Clinical Investigator Team Leadership Awards recognize and support outstanding mid-career clinical investigators at NCI-Designated Cancer Centers who participate extensively in NCI-funded collaborative clinical trials and whose leadership, participation, and activities promote a culture of successful clinical research. This year, 11 investigators nationwide have received the award.

  • Drawing of torso with image of thyroid exposed in neck area and image of thyroid cells in upper left.
    TCGA study improves understanding of genetic drivers of thyroid cancer
    NCI News Note

    (Posted: 10/23/2014) - A comprehensive analysis of the genomes of nearly 500 papillary thyroid carcinomas (PTC) – the most common form of thyroid cancer – has provided new insights into the roles of frequently mutated cancer genes and other genomic alterations that drive disease development, information that may help improve diagnosis and treatment. Findings confirmed that PTCs are driven primarily by mutations in one of two cancer-associated genes: BRAF (and a particular BRAF mutation noted as V600E ) or RAS.

  • Pre-B Acute Lymphoblastic Leukemia cell
    Trial results show high remission rate in leukemia following immune cell therapy
    NCI News Note

    (Posted: 10/12/2014) - Children and young adults (age 1 to age 30) with chemotherapy-resistant B-cell acute lymphoblastic leukemia (ALL) experienced high remission rates following treatment with an experimental immunotherapy. Results demonstrated that the immunotherapy treatment had anti-leukemia effects in patients and that the treatment was feasible and safe.

  • NCI scientists awarded National Medal of Technology and Innovation by President Obama
    NCI News Note

    (Posted: 10/07/2014) - President Obama announced that two NCI scientists would be recipients of the National Medal of Technology and Innovation -- the nation's highest honor for technological achievement. The honorees, John Schiller, Ph.D., Laboratory of Cellular Oncology (LCO), Center for Cancer Research, NCI, and Douglas Lowy, M.D., also from LCO and NCI deputy director, will receive their medals at a White House ceremony later in 2014.

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  • Posted: August 13, 2012
  • Updated: August 13, 2012