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News from NCI
  • Study shows colon and rectal tumors constitute a single type of cancer; The Cancer Genome Atlas generates genomic data for colon and rectal cancers that point to potential targets for treatment
    NCI Press Release

    (Posted: 07/18/2012) - The pattern of genomic alterations in colon and rectal tissues is the same regardless of anatomic location or origin within the colon or the rectum, leading researchers to conclude that these two cancer types can be grouped as one, according to The Cancer Genome Atlas (TCGA) project's large-scale study of colon and rectal cancer tissue specimens.

  • NIH tools facilitate matching cancer drugs with gene targets
    NCI Press Release

    (Posted: 07/16/2012) - A new study details how a suite of web-based tools provides the research community with greatly improved capacity to compare data derived from large collections of genomic information against thousands of drugs. By comparing drugs and genetic targets, researchers can more easily identify pharmaceuticals that could be effective against different forms of cancer.The newly updated software, called CellMiner, was built for use with the NCI-60, one of the most widely utilized collections of cancer cell samples employed in the testing of potential anti-cancer drugs

  • NCI scientists image proteins displayed on HIV surface
    NCI News Note

    (Posted: 07/12/2012) - Using a technique called cryo-electron microscopy, researchers NCI have been able to detect shape changes in a protein called Env that is part of HIV (the human immunodeficiency virus). HIV infection is initiated when Env binds to receptors on host cells.

  • NCI and the Republic of Peru Sign Statement of Intent
    NCI News Note

    (Posted: 06/21/2012) - The U.S. National Cancer Institute and the Republic of Peru signed a statement of intent to share an interest in fostering collaborative biomedical research in oncology and a common goal in educating and training the next generation of cancer research scientists and clinicians.
    View the article in Spanish

  • Cancer survivorship conference highlights research for survivor care: Biennial conference aims to improve quality and length of life for cancer survivors
    NCI Press Release

    (Posted: 06/14/2012) - More than 400 leading experts in cancer survivorship convened today for a conference, Cancer Survivorship Research: Translating Science to Care, to focus on such current concerns as how obesity might not have the same effects on all cancer survivors, and the substantial and increasing economic burden of cancer survivorship in the United States. The conference is jointly sponsored by the American Cancer Society’s Behavioral Research Center, the National Cancer Institute’s Office of Cancer Survivorship, the Lance Armstrong Foundation, and the Centers for Disease Control and Prevention.

  • NIH Human Microbiome Project defines normal bacterial makeup of the body; Genome sequencing creates first reference data for microbes living with healthy adults
    NIH Press Release

    (Posted: 06/13/2012) - Microbes inhabit just about every part of the human body, living on the skin, in the gut, and up the nose. Sometimes they cause sickness, but most of the time, microorganisms live in harmony with their human hosts, providing vital functions essential for human survival. For the first time, a consortium of researchers organized by the National Institutes of Health has mapped the normal microbial make-up of healthy humans, producing numerous insights and even a few surprises.

  • NIH study finds childhood CT scans linked to leukemia and brain cancer later in life
    NCI Press Release

    (Posted: 06/07/2012) - Children and young adults scanned multiple times by computed tomography (CT), a commonly used diagnostic tool, have a small increased risk of leukemia and brain tumors in the decade following their first scan.
    View image View the article in Spanish

  • REMARK checklist elaborated to improve tumor prognostic study reporting
    NCI News Note

    (Posted: 05/29/2012) - Experts have elaborated on a previously published checklist of 20 items -- including descriptions of design, methods, and analysis -- that researchers should address when publishing studies of prognostic markers. These markers are indicators that enable doctors to predict the behavior of a patient’s disease and may aid them in making therapy decisions. The recommendations were originally developed and published simultaneously in five journals in August 2005, to address widespread deficiencies in reporting of such studies, which sometimes has led to inaccurate or irreproducible conclusions.

  • The Prostate, Lung, Colorectal, and Ovarian (PLCO) Cancer Screening Trial: Questions and Answers

    (Posted: 05/21/2012) - The Prostate, Lung, Colorectal and Ovarian (PLCO) Cancer Screening Trial is a large, randomized study to determine whether the use of certain screening tests will reduce the risk of dying of those four cancers. In addition to answering questions about the screening tests, the PLCO asked questions about many aspects of the study participants’ health and collected biospecimens (blood and some tissues) to answer many other questions about cancer.
    View the article in Spanish

  • NIH study finds sigmoidoscopy reduces colorectal cancer rates
    NCI Press Release

    (Posted: 05/21/2012) - Study finds that flexible sigmoidoscopy is effective in reducing the rates of new cases and deaths due to colorectal cancer. Researchers found that overall colorectal cancer mortality was reduced by 26 percent and incidence was reduced by 21 percent as a result of screening with sigmoidoscopy.
    Questions & Answers View image Play video View the article in Spanish

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