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News from NCI

  • A black and white line drawing of a fallopian tube, which looks like an elongated trumpet flower
    NCI study examines outcomes from surgery to prevent ovarian cancer
    NCI News Note

    (Posted: 09/08/2014) - A new study looked at women at high risk of ovarian cancer who had no clinical signs of the disease and who underwent risk-reducing salpingo-oophorectomy (RRSO). The study results showed cancer in the removed tissues of 2.6 percent (25 of 966) of the participants.

  • Risk factors identified for certain lymphoma subtypes
    NCI News Note

    (Posted: 09/02/2014) - In a large international collaborative analysis of risk factors for non-Hodgkin lymphoma (NHL), scientists were able to quantify risk associated with medical history, lifestyle factors, family history of blood or lymph-borne cancers, and occupation for 11 different NHL subtypes, including less common subtypes.

  • Credit:Sang Eun Lee (Samsung Medical Center).  Illustration shows chromophobe renal cell carcinoma (a rare type of kidney tumor) highlighting important roles for mtDNA mutations and structural alterations involving TERT promoters as white dots on a purple background
    Rare kidney tumor provides insights on role of metabolic changes in cancer
    NCI News Note

    (Posted: 08/21/2014) - Researchers in The Cancer Genome Atlas (TCGA) Network have uncovered a number of new findings about the biology and development of a rare form of kidney cancer. They found that the disease – chromophobe renal cell carcinoma – stems in part from alterations in genes in the mitochondria, the cell’s energy supplier.

  • NIH announces the launch of 3 integrated precision medicine trials; ALCHEMIST is for patients with certain types of early-stage lung cancer
    NCI Press Release

    (Posted: 08/18/2014) - The Adjuvant Lung Cancer Enrichment Marker Identification and Sequencing Trials, or ALCHEMIST, will identify early-stage lung cancer patients with tumors that harbor certain uncommon genetic changes and evaluate whether drug treatments targeted against those changes can lead to improved survival.
    Questions & Answers View the article in Spanish

  • A grid of blue and red rectangles, with Pan-Cancer integrated subtypes with high scores depicted in red, indicating over-activity, while low scores are depicted in blue, indicating lower activity compared to normal, and with lines interconnecting commonalities
    The benefits of looking across many cancer genomes: A perspective
    NCI Perspective

    (Posted: 09/27/2013, Updated: 08/12/2014) - Cancer is not a single entity, but rather, it is more than one hundred complex and distinct diseases, with most cancer types demanding a unique treatment strategy. TCGA researchers have developed a formal project for a cross tumor analysis, called Pan-Cancer. Its goal is to assemble TCGA’s wealth of data across tumor types, analyze and interpret those data, and finally, make both the analyses and the data freely available.

  • Blue, red, purple and orange image of a glutamate receptor
    Molecular mechanism identified for activation and desensitization of prominent neurotransmitter receptor in the brain
    NCI News Note

    (Posted: 08/04/2014) - Scientists at the NIH have used a technique called cryo-electron microscopy to determine a molecular mechanism for the activation and desensitization of ionotropic glutamate receptors, a prominent class of neurotransmitter receptors in the brain and spinal cord that have also been implicated in some cancers.

  • NCI Community Oncology Research Program (NCORP) Gets Underway
    NCI News Note

    (Posted: 08/01/2014) - NCI has awarded 53 new 5-year grants to researchers across the country to conduct multi-site cancer clinical trials and cancer care delivery research studies in their communities. The grants are being awarded under the NCI Community Oncology Research Program (NCORP)
    View the article in Spanish

  • NCI Statement on the U.S. Surgeon General's "Call to Action to Prevent Skin Cancer"

    (Posted: 07/29/2014) - As the Federal Government's principal agency for cancer research and training, the National Cancer Institute (NCI) endorses the U.S. Surgeon General’s “Call to Action to Prevent Skin Cancer,” which provides a comprehensive evaluation of the current state of skin cancer prevention efforts in the United States and recommends actions for improvement in the future.

  • A drawing of the stomach with four icons included: DNA spirals, paired chromosomes, cells with nuclei, and a core diamond representing key subtypes
    TCGA researchers identify four subtypes of stomach cancer
    NCI Press Release

    (Posted: 07/23/2014) - Stomach cancers fall into four distinct molecular subtypes, researchers with The Cancer Genome Atlas (TCGA) Network have found. Scientists report that this discovery could change how researchers think about developing treatments for stomach cancer, also called gastric cancers or gastric adenocarcinomas.

  • Three circles of colorectal cancer slides, blue and orange, purple and white and other red and green – all  on a black background.
    Researchers report first large-scale integrated proteomic and genomic analysis of a human cancer: Identification of new molecular features of colorectal cancer
    NCI News Note

    (Posted: 07/21/2014) - Investigators who analyzed 95 human colorectal tumor samples have determined how gene alterations identified in previous analyses of the same samples are expressed at the protein level. The integration of proteomic and genomic data, or proteogenomics, provides a more comprehensive view of the biological features that drive cancer than genomic analysis alone.

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  • Posted: August 13, 2012
  • Updated: August 13, 2012