NCI Drug Dictionary

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The NCI Drug Dictionary contains technical definitions and synonyms for drugs/agents used to treat patients with cancer or conditions related to cancer. Each drug entry includes links to check for clinical trials listed in NCI's List of Cancer Clinical Trials.

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rilimogene galvacirepvec
A vaccine formulation consisting of recombinant vaccinia virus encoding prostate specific antigen (PSA) and recombinant vaccinia virus encoding three co-stimulatory molecule transgenes B7.1, ICAM-1, and LFA-3 (TRICOM). Vaccination with PSA in combination with TRICOM may enhance antigen presentation, resulting in the augmentation of a cytotoxic T cell (CTL) immune response against tumor cells expressing PSA. Check for active clinical trials using this agent. (NCI Thesaurus)

Synonym:PROSTVAC-V
PROSTVAC-V/TRICOM
recombinant vaccinia-PSA(L155)/TRICOM vaccine
rvaccinia-prostate-specific antigen-TRICOM vaccine
rvaccinia-PSA-TRICOM vaccine
Abbreviation:vPSA-TRI