NCI Drug Dictionary

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The NCI Drug Dictionary contains technical definitions and synonyms for drugs/agents used to treat patients with cancer or conditions related to cancer. Each drug entry includes links to check for clinical trials listed in NCI's List of Cancer Clinical Trials.

girentuximab
A chimeric monoclonal antibody directed against G250, a cell surface antigen found in the majority of renal cell carcinomas. Following binding, girentuximab may be internalized by G250 antigen-expressing renal carcinoma cells; mAb G250 may be useful as a carrier for radioisotopes and other antineoplastic therapeutic agents. Check for active clinical trials using this agent. (NCI Thesaurus)
Synonyms:chimeric monoclonal antibody cG250
monoclonal antibody G-250
WX-G250
US brand name:Rencarex
Abbreviations:cG250
MOAB G250