NCI Drug Dictionary

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The NCI Drug Dictionary contains technical definitions and synonyms for drugs/agents used to treat patients with cancer or conditions related to cancer. Each drug entry includes links to check for clinical trials listed in NCI's List of Cancer Clinical Trials.

norgestrel
A synthetic progestin commonly used alone or in combination with an estrogen for contraception. Norgestrel suppresses the secretion of luteinizing and follicle-stimulating hormones (LH and FSH), thickens cervical mucus, and slows the transit of ova through the fallopian tubes. This agent also exhibits antiproliferative activity in endometrial tissue and may exhibit chemopreventive and antineoplastic activities in endometrial carcinoma. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Synonyms:D-(-)-Norgestrel
Levonorgestrel
US brand names:Neogest
Ovrette
Foreign brand name:Microlut
Abbreviation:NORGES
Code name:Wy-3707
Chemical structures:(+/-)-13-ethyl-17alpha-hydroxy-18,19-dinorpregn-4-en-20-yne-3-one
(17alpha)-13-ethyl-17-hydroxy-18,19-dinorpregn-4-en-20-yn-3-one