NCI Drug Dictionary

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The NCI Drug Dictionary contains technical definitions and synonyms for drugs/agents used to treat patients with cancer or conditions related to cancer. Each drug entry includes links to check for clinical trials listed in NCI's List of Cancer Clinical Trials.

volociximab
A chimeric monoclonal antibody with potential antineoplastic activity. Volociximab binds to and inhibits the activity of alpha(5)beta(1) integrin, thereby inhibiting endothelial cell-cell interactions, endothelial cell-matrix interactions, and angiogenesis. Check for active clinical trials using this agent. (NCI Thesaurus)
Synonyms:anti-alpha 5 beta 1 integrin monoclonal antibody
anti-α5β1 integrin
Abbreviation:anti-α5β1 integrin MOAB
Code name:M200