NCI Dictionary of Cancer Terms

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The NCI Dictionary of Cancer Terms features 7,919 terms related to cancer and medicine.

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hyperkeratosis
(HY-per-KAYR-uh-TOH-sis)
A condition marked by thickening of the outer layer of the skin, which is made of keratin (a tough, protective protein). It can result from normal use (corns, calluses), chronic inflammation (eczema), or genetic disorders (X-linked ichthyosis, ichthyosis vulgaris).