NCI Dictionary of Cancer Terms

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The NCI Dictionary of Cancer Terms features 7,791 terms related to cancer and medicine.

Browse the dictionary by selecting a letter of the alphabet or by entering a cancer-related word or phrase in the search box.

anti-platelet-derived growth factor receptor alpha monoclonal antibody IMC-3G3
(AN-tee-PLAYT-let-deh-RIVED grothe FAK-ter reh-SEP-ter AL-fuh MAH-noh-KLOH-nul AN-tee-BAH-dee …)
A substance being studied in the treatment of glioblastoma (a type of brain tumor) that has come back. It binds to receptors for a protein called platelet-derived growth factor (PDGF). This keeps PDGF from binding to the cells. This may stop the growth of cancer cells and blood vessels that have the receptors for PDGF. It is a type of monoclonal antibody. Also called anti-PDGFR alpha monoclonal antibody IMC-3G3 and IMC-3G3.