NCI Dictionary of Cancer Terms
The NCI Dictionary of Cancer Terms features 7,800 terms related to cancer and medicine.
Browse the dictionary by selecting a letter of the alphabet or by entering a cancer-related word or phrase in the search box.
- BRAF (V600E) kinase inhibitor RO5185426
- listen (… KY-nays in-HIH-bih-ter …)
A drug used to treat advanced melanoma that has a mutated (changed) form of a cell protein called BRAF. It is also being studied in the treatment of other types of cancer. BRAF (V600E) kinase inhibitor RO5185426
blocks this mutated protein, which may stop the growth of cancer cells. It is a type of kinase inhibitor and a type of targeted therapy agent. Also called PLX4032, RG7204, vemurafenib, and Zelboraf.