NCI Dictionary of Genetics Terms

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Welcome to the NCI Dictionary of Genetics Terms, which contains technical definitions for more than 150 terms related to genetics. These definitions were developed by the PDQ® Cancer Genetics Editorial Board to support the evidence-based, peer-reviewed PDQ cancer genetics information summaries.

proband
(PROH-band)
The individual through whom a family with a genetic disorder is ascertained. In males this is called a propositus, and in females it is called a proposita.