NCI Dictionary of Genetics Terms

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Welcome to the NCI Dictionary of Genetics Terms, which contains technical definitions for more than 150 terms related to genetics. These definitions were developed by the PDQ® Cancer Genetics Editorial Board to support the evidence-based, peer-reviewed PDQ cancer genetics information summaries.

Crohn disease-like reaction
(krone dih-ZEEZ-like ree-AK-shun)
Discrete aggregates of lymphoid white blood cells, some with germinal centers and surrounding fibrosis, commonly found around some colorectal adenocarcinomas in the absence of a clinical or pathological diagnosis of Crohn disease. Also called Crohn-like reaction.