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Harold C. Simmons Cancer Center
University of Texas Southwestern Medical Center
Dallas, Texas

The Harold C. Simmons Cancer Center at the University of Texas (UT) Southwestern Medical Center was established in 1991 and received its NCI designation in 2010. The Center has built on a basic science foundation and developed a focus on translational cancer research.

The Simmons Cancer Center provides patients living in the Dallas-Fort Worth Metroplex and North Texas with access to innovative cancer treatment. To accomplish this, the Center has brought together 214 members from 34 departments and centers across the University to promote innovations in cancer diagnosis, treatment, and control. The members work in trans-disciplinary teams on research organized around four scientific programs: Chemistry and Cancer, Development and Cancer, Cancer Cell Networks, and Molecular Therapeutics of Cancer. There is also a developing program in Population Science and Cancer Control.

The Chemistry and Cancer program focuses on discovery of drug-like chemicals that affect biological processes related to the development or inhibition of cancer. The Development and Cancer program brings together investigators in cancer biology, stem cell biology, and developmental biology to uncover how aberrant developmental processes contribute to the initiation and progression of cancer. The Cancer Cell Networks program promotes research to increase understanding of the mechanisms in aberrant cell regulatory networks that support cancer initiation and growth. The Molecular Therapeutics of Cancer program advances personalized medicine in cancer care by understanding how gene-related processes lead to cancer, and how genetic variation among individuals affects tumor growth and response to treatment.

Patient care is provided at UT Southwestern clinics and hospitals in addition to Parkland Hospital and the Children’s Medical Center. In addition to receiving care, patients may also participate in a wide range of clinical trials. The Center’s Moncrief Cancer Institute, located in Fort Worth, extends the Center’s community outreach activities to Fort Worth and surrounding rural counties. There is also a clinical genetics screening program that offers counseling to high-risk individuals in North Texas. Students enrolled in the UT Southwestern Graduate School of Biomedical Sciences can pursue a Ph.D. in Cancer Biology.

* This profile was provided by the Harold C. Simmons Cancer Center.

Harold C. Simmons Cancer Center
Cancer Center

James K. V. Willson, M.D.

2201 Inwood Road
Dallas, Texas 75390
Main: (214) 645-4673 (214-645-HOPE)
Toll Free: 1-866-460-4673 (1-866-460-HOPE)

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  • Updated: July 26, 2012