Introduction
NCI Special Notes
Funded R25T Grants
Submitting an Application
Peer Review Process
Frequently Asked Questions
NCI Staff Contacts
Introduction
The Cancer Education and Career Development Program (R25T) supports the development and implementation of curriculum-dependent programs to train predoctoral and postdoctoral candidates in cancer research settings that are highly inter-disciplinary and collaborative. This program is particularly applicable to cancer prevention and control, epidemiology, nutrition, and the behavioral and population sciences, but should also be considered by other interdisciplinary areas of research such as imaging and molecular diagnosis that will require sustained leadership, interdisciplinary research environments, and more than one mentor per program participant to achieve their education and research career development objectives.
The Principal Investigator must be an established investigator in a field relevant to the objectives and purpose of the Program and able to provide both administrative and scientific leadership. Candidates may be predoctoral or postdoctorals. They usually must be (see exception below) citizens or non-citizen nationals of the United States, or must have been lawfully admitted to the United States for permanent residence (i.e., in possession of a currently valid Alien Registration Receipt Card I-551, or other legal verification of such status), but, under exceptional circumstances, the R25T does allow for the training of foreign nationals. These require NCI approval of individuals on a case-by-case basis and would always depend upon the special international, collaborative nature of the research areas that the training and Career Development Program emphasizes.
The R25T grant mechanism provides up to five years of support and is renewable. These grants support salary (up to $20,000 per year for predoctorals and $75,000 per year for postdoctorals), research development support (up to $20,000 for predoctorals and up to $30,000 per year for postdoctorals), advertising and recruitment costs, ancillary personnel costs, and facilities and administrative costs (formerly called indirect costs).
PAR-06-511 CANCER EDUCATION AND CAREER DEVELOPMENT PROGRAM (R25T)
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NCI Special Notes
Suggested tabular formats for presenting data on trainees are provided for your convenience. "Click on" TABLES (Word for Windows) or TABLES (PDF), which ever you prefer, to download this information.
The National Cancer Institute (NCI) Cancer Education and Career Development Program (R25T) must be in compliance with all NIH/NCI policies pertaining to the use of human subjects. These policies apply to all research involving human subjects, not just clinical trials. The R25T is a training and career development grant in which candidate positions are filled at the discretion of the institution and assignment of candidate positions is generally not known at the time of application or at the time of an award. Due to this uncertainty, the word "Indefinite" should be placed in the box for IRB review date on the face page of the application and the applicant institution must provide in the submitted grant application a Special Statement on Human Subjects Research.
The complete Special Institutional Statement Regarding Human Subjects Research Under R25T Support may be accessed by clicking
R25T Special Institutional Statement Regarding Human Subjects Research.
Inquiries are encouraged, and the opportunity to clarify any issues or questions is welcome. Inquiries should be sent to:
Dr. Dorkina Myrick
Cancer Training Branch
National Cancer Institute
6116 Executive Boulevard, Suite 7019
Rockville, MD 20852 (overnight mail)
Bethesda, MD 20892?8346 (regular mail)
Telephone: (301) 496-8580
FAX: (301) 402-4472
Email: myrickd@mail.nih.gov
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Funded R25T Grants
The Cancer Education and Career Development Program (R25T) supports the development and implementation of curriculum-dependent programs to train predoctoral and postdoctoral candidates in cancer research settings that are highly inter-disciplinary and collaborative.
See the NCI Funded Research Portfolio for a current list of R25T funded grants.
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Submitting an Application
|
| Application Receipt Date: New, Renewal*, Revision*, and Resubmission* |
Initial Review Date |
Council Review Date |
Earliest Possible Start Date ** |
| Receipt Cycle 1 |
January 25 |
June/July |
September/ October |
December |
| Receipt Cycle 2 |
May 25 |
October/November |
January/ February |
April |
| Receipt Cycle 3 |
September 25 |
February/March |
May/June |
July |
* The move to electronic applications also has brought a change in terminology. The new Grants.gov terminology (included in the table above) corresponds to traditional NIH terms as follows:
- New = new
- Resubmission = a revised or amended application
- Renewal = Competing Continuation
- Continuation = Progress Report
- Revision = Competing Supplement
If the application receipt date falls on a weekend, the application must be postmarked by the application receipt date and received at the Center for Scientific Review (CSR) by the following Monday.
If the application receipt date falls on a holiday, (but not on a weekend), the application must be postmarked by the application receipt date and received at CSR by the following day.
** Start dates are determined by the availability of NCI funds and may not occur until well after the earliest possible start date.
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Peer Review Process
Upon receipt, competing applications will be reviewed both by the Center for Scientific Review (CSR) and the National Cancer Institute (NCI) for completeness and for conformance to all eligibility requirements and special provisions and requirements. Incomplete applications will be returned to the applicant without further consideration.
Those applications judged to be complete and eligible will be evaluated, according to the review criteria listed in the Program Announcement, by Subcommittee G convened by the Division of Extramural Activities of the NCI. Applications will receive a second level review by the National Cancer Advisory Board (NCAB) to determine if the application meets the broad program needs and priorities of the NCI and the National Cancer Program.
For review criteria for the R25T grant mechanism, see the Review Criteria section of the Program Announcement.
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Frequently Asked Questions
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How many trainees can be supported by an R25T grant?
The answer to this question is currently under revision. Please check back to this site for a revised answer in the next few days.
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Who should be on the Advisory Committee?
The answer to this question is currently under revision. Please check back to this site for a revised answer in the next few days.
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Since human subjects may be involved in the R25T program, must each trainee obtain his/her own IRB approval?
If the trainee will be participating in a larger research program that already has received IRB approval, new IRB approval is not needed. If the research proposed is not part of an ongoing research project with an IRB approval, new IRB approval is needed.
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Is there a preference in the disciplines represented in the R25T program?
The answer to this question is currently under revision. Please check back to this site for a revised answer in the next few days.
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Can the trainee's salary be supplemented?
Yes, but only from non-PHS sources for work that is the same as being supported by the R25T. A trainee can be compensated for work while receiving salary from the R25T grant from any source as long as his/her total percent effort does not exceed 100 percent and the work is unrelated to the work being supported by the R25T.
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If we have an existing curriculum that will serve the R25T program, can we still apply?
No. One of the main premises of this award is that there are not sufficient curricula available to compliment the research training experiences of an R25T program.
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Can an R25T grant be awarded for less than 5 years?
The answer to this question is currently under revision. Please check back to this site for a revised answer in the next few days.
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What are the R25T requirements for Training in the Responsible Conduct of Research?
R25T grants do not have any mandatory requirements. However, it is strongly recommended that trainees deficient in this area who will be conducting clinical research with human subjects during their appointment obtain training in the responsible conduct of research.
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How many faculty members should I have in the program?
You should have a sufficient number of faculty members to adequately address the proposed education and research training needs of the program. Trainees need multiple mentors, so the number of members who participate in the R25T
program would be large. In addition, some faculty might participate in the design and implementation of specialized curriculum but not serve as mentors. The number of faculty involved could be large and diversified.
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Should the mentors be mainly senior individuals?
The answer to this question is currently under revision. Please check back to this site for a revised answer in the next few days.
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Will my grant application be reviewed by a CSR peer review group?
No. Applications for the NCI Cancer Education and Career Development Program (R25T) are reviewed by an NCI initial review group that is composed specially to review multidisciplinary training and career development needs.
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What should my application contain if it deals with human subjects, clinical trials or vertebrate animals?
Applicants should submit a Special Institutional Statement Regarding Human Subjects Research under R25T Support for all applications in which clinical trials are conducted. This statement must be submitted to NCI program staff for approval before the initial grant award can be issued and resubmitted with each "Application for a Continuation Grant."
The applicant must also include an abbreviated Data and Safety-Monitoring (DSM) plan showing that the sponsoring institution has established standards for data and safety monitoring of clinical trials.
Please follow the instructions in the Vertebrate Animals section of the instructions for preparing a SF 424 (R&R) Application Guide if vertebrate animals are used.
An award cannot be made without proper information on Gender and Minority Inclusion, Inclusion of Children, and Vertebrate Animals. The applicant must also obtain human subject IRB certification and provide this information to the NCI before an award is made. Furthermore, if appropriate, a detailed DSM plan must also be provided.
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Can the support provided for OTHER EXPENSES be used to offset costs incurred in advertising and recruiting for the program?
Yes. A small proportion of the budget can be used for advertising and recruiting the best candidates for the program. This kind of expense is usually not allowed on grants devoted to education, training, and career development.
However, we expect that many of the programs supported by the R25T will involve multiple departments and schools and that recruitment to these very special programs will require additional efforts that are not part of the usual business of an institution.
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Does the NCI R25T grant operate under Expanded Authority?
Yes, except in one area. Automatic carryover of unexpended funds is not permitted. If there is a need for carryover, prior approval by the Grants Administration Staff of the NCI is required. Under most circumstances, each R25T is fully funded each year and there is little need for carryovers.
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If I have an R25T award and would like to ask for post award changes, how do I go about this?
You must contact the NCI Grants Administration official to determine the appropriate procedures to use in making a request for post award changes in your grant. This also applies to any of your needs that require a prior approval from the NCI. In general, you will have to make a request that is signed by you and a business official of your institution. After receiving the request, the Grants Administration official will consult with the NCI scientific program staff as necessary to determine whether the request can be approved.
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NCI Staff Contacts
For additional information regarding policies and/or guidance in preparing an application for the R25T Award, contact:
Dr. Shannon M. Lemrow
Program Director
Telephone: (301) 496-8580
Fax: (301) 480-1744
E-mail: lemrows@mail.nih.gov
Dr. Dorkina Myrick
Program Director
Telephone: (301) 496-8580
Fax: (301) 480-1744
E-mail: myrickd@mail.nih.gov
For information regarding fiscal and/or budget issues, contact:
Grants Administration Branch
Phone: (301) 496-7208
Fax: (301) 496-8601
For information regarding review issues, contact:
Referral Officer
Division of Extramural Activities
Telephone: (301) 594-1403
Fax: (301) 402-0275
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