Policy-Related
Application Process/Review Related
Policy/Post Award

Policy-Related

1. How many trainees can be supported by an R25T grant?
   The answer to this question is currently under revision. Please check back to this site for a revised answer in the next few days.

2. Who should be on the Advisory Committee?
   The answer to this question is currently under revision. Please check back to this site for a revised answer in the next few days.

3. Since human subjects may be involved in the R25T program, must each trainee obtain his/her own IRB approval?
   If the trainee will be participating in a larger research program that already has received IRB approval, new IRB approval is not needed. If the research proposed is not part of an ongoing research project with an IRB approval, new IRB approval is needed.

4. Is there a preference in the disciplines represented in the R25T program?
   The answer to this question is currently under revision. Please check back to this site for a revised answer in the next few days.

5. Can the trainee's salary be supplemented?
   Yes, but only from non-PHS sources for work that is the same as being supported by the R25T. A trainee can be compensated for work while receiving salary from the R25T grant from any source as long as his/her total percent effort does not exceed 100 percent and the work is unrelated to the work being supported by the R25T.

6. If we have an existing curriculum that will serve the R25T program, can we still apply?
   No. One of the main premises of this award is that there are not sufficient curricula available to compliment the research training experiences of an R25T program.

7. Can an R25T grant be awarded for less than 5 years?
   The answer to this question is currently under revision. Please check back to this site for a revised answer in the next few days.

8. What are the R25T requirements for Training in the Responsible Conduct of Research?
   R25T grants do not have any mandatory requirements. However, it is strongly recommended that trainees deficient in this area who will be conducting clinical research with human subjects during their appointment obtain training in the responsible conduct of research.

9. How many faculty members should I have in the program?
   You should have a sufficient number of faculty members to adequately address the proposed education and research training needs of the program. Trainees need multiple mentors, so the number of members who participate in the R25T program would be large. In addition, some faculty might participate in the design and implementation of specialized curriculum but not serve as mentors. The number of faculty involved could be large and diversified.

10. Should the mentors be mainly senior individuals?
    The answer to this question is currently under revision. Please check back to this site for a revised answer in the next few days.

Application Process/Review Related

11. Will my grant application be reviewed by a CSR peer review group?
    No. Applications for the NCI Cancer Education and Career Development Program (R25T) are reviewed by an NCI initial review group that is composed specially to review multidisciplinary training and career development needs.

12. What should my application contain if it deals with human subjects, clinical trials or vertebrate animals?
    Applicants should submit a Special Institutional Statement Regarding Human Subjects Research under R25T Support for all applications in which clinical trials are conducted. This statement must be submitted to NCI program staff for approval before the initial grant award can be issued and resubmitted with each "Application for a Continuation Grant."

    The applicant must also include an abbreviated Data and Safety-Monitoring (DSM) plan showing that the sponsoring institution has established standards for data and safety monitoring of clinical trials.

    Please follow the instructions in the Vertebrate Animals section of the instructions for preparing a SF 424 (R&R) Application Guide if vertebrate animals are used.

    An award cannot be made without proper information on Gender and Minority Inclusion, Inclusion of Children, and Vertebrate Animals. The applicant must also obtain human subject IRB certification and provide this information to the NCI before an award is made. Furthermore, if appropriate, a detailed DSM plan must also be provided.

Policy/Award Related

13. Can the support provided for OTHER EXPENSES be used to offset costs incurred in advertising and recruiting for the program?
    Yes. A small proportion of the budget can be used for advertising and recruiting the best candidates for the program. This kind of expense is usually not allowed on grants devoted to education, training, and career development. However, we expect that many of the programs supported by the R25T will involve multiple departments and schools and that recruitment to these very special programs will require additional efforts that are not part of the usual business of an institution.

14. Does the NCI R25T grant operate under Expanded Authority?
    Yes, except in one area. Automatic carryover of unexpended funds is not permitted. If there is a need for carryover, prior approval by the Grants Administration Staff of the NCI is required. Under most circumstances, each R25T is fully funded each year and there is little need for carryovers.

15. If I have an R25T award and would like to ask for post award changes, how do I go about this?
    You must contact the NCI Grants Administration official to determine the appropriate procedures to use in making a request for post award changes in your grant. This also applies to any of your needs that require a prior approval from the NCI. In general, you will have to make a request that is signed by you and a business official of your institution. After receiving the request, the Grants Administration official will consult with the NCI scientific program staff as necessary to determine whether the request can be approved.

Back to Top

< Previous Section  |  Next Section >