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Alternate Title
Basic Trial Information
Trial Description
     Purpose
     Eligibility
     Treatment/Intervention
Trial Contact Information
Registry Information

Alternate Title

Randomized Screening Study of CA 125 and Ultrasound in the Detection of Ovarian Cancer in Postmenopausal Women

Basic Trial Information

Phase	Type	Status	Age	Sponsor	Protocol IDs
No phase specified	Screening	Closed	50 to 74	Other	UKCTOCS EU-20249, NCT00058032

Trial Description

Purpose:

Screening tests may help doctors detect cancer cells early and plan more effective treatment for cancer. It is not yet known if ultrasound is more effective with or without measuring CA 125 levels in detecting ovarian cancer in postmenopausal women.

Randomized clinical trial to study the effectiveness of ultrasound with or without measuring CA 125 levels in detecting ovarian cancer in postmenopausal women.

Eligibility:

Eligibility criteria include the following:

• 50-74 years old
• No previous ovarian cancer
• No previous surgery to remove both ovaries
• For more information about the eligibility criteria for this trial, refer to the Health Professional version.

Final eligibility for a clinical trial is determined by the health professionals conducting the trial.

Treatment/Intervention:

Participants will be randomly assigned to one of three groups.

As part of the study, participants in group one will not be screened for ovarian cancer using CA 125 levels or ultrasound.

Participants in group two will have CA 125 levels measured and will undergo ultrasound.

Participants in group three will undergo ultrasound followed 6-8 weeks later by a repeat ultrasound.

All participants will complete questionnaires at 3.5 and 7 years.

Important:

For more details about this trial, refer to the Health Professional version of the trial summary.

If you are interested in participating in a clinical trial, contact your doctor for a referral or call a trial contact person listed below. You may see the same contact person listed at more than one site, however, if you call the number listed you can ask to speak to the study coordinator or person involved with the specific trial you are interested in. If you have questions about cancer or clinical trials, call the Cancer Information Service at 1-800-4-CANCER (1-800-422-6237). General information about clinical trials, including risks, benefits, and costs, can be found on NCI's Web site.

Trial Contact Information

Trial Lead Organizations

Saint Bartholomew's Hospital

Usha Menon, MBBS, MRCOG, Protocol chair(Contact information may not be current)		Ph: 44-20-7882-5955 Email: u.menon@ucl.ac.uk

Registry Information
Official Title		United Kingdom Collaborative Trial Of Ovarian Cancer Screening
Trial Start Date		2003-02-13
Registered in ClinicalTrials.gov		NCT00058032
Date Submitted to PDQ		2003-02-12
Information Last Verified		2005-09-27

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