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Alternate Title
Basic Trial Information
Trial Description
     Purpose
     Eligibility
     Treatment/Intervention
Trial Contact Information
Registry Information

Alternate Title

Phase II Pilot Study of Fluorouracil/Leucovorin Calcium/Cisplatin (FLEP) in Profoundly Immunosuppressed Patients with AIDS-Related Lymphoma (Summary Last Modified 08/2000)

Basic Trial Information

Phase	Type	Status	Age	Sponsor	Protocol IDs
Phase II	Treatment	Closed	over 15	NCI	MDA-DM-93058 NCI-T93-0088D, NCT00002524, T93-0088

Trial Description

Purpose:

Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining more than one drug may kill more cancer cells.

Phase II trial to study the effectiveness of combination chemotherapy in treating patients with AIDS -related lymphoma.

Eligibility:

• At least 16 years old
• Previously untreated lymphoma
• No previously diagnosed Kaposi's sarcoma
• For more information about the eligibility criteria for this trial, refer to the Health Professional version.

Final eligibility for a clinical trial is determined by the health professionals conducting the trial.

Treatment/Intervention:

Patients will receive combination chemotherapy over a period of 1-5 days. Treatment will be repeated every 3 weeks for three to six courses. Some patients will receive radiation therapy before and/or after chemotherapy. Patients will receive follow-up evaluations every 3 months for 1 year, every 4 months for 1 year, and every 6-12 months thereafter.

Important:

For more details about this trial, refer to the Health Professional version of the trial summary.

If you are interested in participating in a clinical trial, contact your doctor for a referral or call a trial contact person listed below. You may see the same contact person listed at more than one site, however, if you call the number listed you can ask to speak to the study coordinator or person involved with the specific trial you are interested in. If you have questions about cancer or clinical trials, call the Cancer Information Service at 1-800-4-CANCER (1-800-422-6237). General information about clinical trials, including risks, benefits, and costs, can be found on NCI's Web site.

Trial Contact Information

Trial Lead Organizations

M. D. Anderson Cancer Center at University of Texas

Peter McLaughlin, MD, Protocol chair		Ph: 713-792-2860; 800-392-1611 Email: pmclaugh@mdanderson.org

Registry Information
Official Title		PILOT STUDY IN AIDS-RELATED LYMPHOMAS
Trial Start Date		1993-06-28
Registered in ClinicalTrials.gov		NCT00002524
Date Submitted to PDQ		1993-06-28
Information Last Verified		2000-08-01

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