- A drug that works in a different way than a steroid to reduce pain, redness, swelling, and fever in the body. Some NSAIDs may also help keep blood clots from forming. The side effects of NSAIDs include bleeding and stomach, kidney, and heart problems. Examples of NSAIDs are aspirin, ibuprofen, ketoprofen, celecoxib, diclofenac, and ketorolac. NSAIDs may also help prevent some types of cancer. Also called nonsteroidal anti-inflammatory drug.