A drug used to treat many types of cancer, including Hodgkin lymphoma, non-Hodgkin lymphoma, penile cancer, testicular cancer, and squamous cell carcinoma of the cervix, head and neck, and vulva. It is also used to treat malignant pleural effusion. It is also being studied in the treatment of other types of cancer. Bleomycin sulfate comes from the bacterium Streptomyces verticillus. It damages the cell’s DNA and may kill cancer cells. It is a type of antineoplastic antibiotic. Bleomycin is the active ingredient of bleomycin sulfate.