stage II esophageal adenocarcinoma (... ee-SAH-fuh-JEE-ul A-deh-noh-KAR-sih-NOH-muh)
Stage II is divided into stages IIA and IIB, depending on where the cancer has spread. In stage IIA, cancer has spread into the thick muscle layer of the esophagus wall. The cancer cells are grade 3 or the grade is not known. Grade 3 cancer cells look more abnormal under a microscope and grow and spread more quickly than grade 1 and 2 cancer cells. In stage IIB, cancer has spread (1) into the connective tissue layer of the esophagus wall; or (2) into the mucosa layer, thin muscle layer, or submucosa layer of the esophagus wall. Cancer is found in 1 or 2 lymph nodes near the tumor.