Clinical Trials Using Digoxin

Clinical trials are research studies that involve people. The clinical trials on this list are studying Digoxin. All trials on the list are supported by NCI.

NCI’s basic information about clinical trials explains the types and phases of trials and how they are carried out. Clinical trials look at new ways to prevent, detect, or treat disease. You may want to think about taking part in a clinical trial. Talk to your doctor for help in deciding if one is right for you.

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  • Neoadjuvant Chemotherapy and Digoxin for the Treatment of Resectable Pancreatic Cancer

    This phase IIa trial studies how well neoadjuvant chemotherapy and digoxin work in treating patients with pancreatic cancer that can be removed by surgery (resectable). Drugs used in chemotherapy, such as fluorouracil, irinotecan, leucovorin calcium, and oxaliplatin, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Digoxin may improve cancer drugs effect and slow tumor growth. Given neoadjuvant chemotherapy and digoxin together may work better in treating patients with resectable pancreatic cancer compared to chemotherapy alone.
    Location: University of Nebraska Medical Center, Omaha, Nebraska