Clinical Trials Using Fluorescent Imaging Ligand OTL38

Clinical trials are research studies that involve people. The clinical trials on this list are studying Fluorescent Imaging Ligand OTL38. All trials on the list are supported by NCI.

NCI’s basic information about clinical trials explains the types and phases of trials and how they are carried out. Clinical trials look at new ways to prevent, detect, or treat disease. You may want to think about taking part in a clinical trial. Talk to your doctor for help in deciding if one is right for you.

Trials 1-2 of 2
  • Intraoperative Imaging using OTL38 in Diagnosing Patients with Lung or Pleura Nodules Undergoing Surgery

    This phase II trial studies intraoperative imaging using fluorescent imaging ligand OTL38 (OTL38) in diagnosing patients with lung or pleura nodules undergoing surgery. Drugs, such as OTL38, attach to the cancer and "mark" it. During surgery, the surgeons hold a camera system over the nodule that will excite OTL38. Imaging during surgery may cause the nodule to glow, thus "marking" the cancer and making it easier for surgeons to remove.
    Location: University of Pennsylvania / Abramson Cancer Center, Philadelphia, Pennsylvania

  • OTL38 for Intra-operative Imaging of Folate Receptor Positive Ovarian Cancer

    This is a phase 3, randomized, multi-center, single dose, open label, pivotal study in patients diagnosed with, or with high clinical suspicion of, ovarian cancer scheduled to undergo primary surgical cytoreduction, interval debulking, or recurrent ovarian cancer surgery.
    Location: 9 locations